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Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache
BACKGROUND: Triptans are only effective in terminating cluster headache (CH) attacks in 70-80% of patients. Pharmacogenetic aspects of the serotonin metabolism, specifically variation in the 5-HTTLPR may be involved. METHODS: Genetic association study in a well-defined cohort of 148 CH patients with...
Autores principales: | Schürks, Markus, Frahnow, Antje, Diener, Hans-Christoph, Kurth, Tobias, Rosskopf, Dieter, Grabe, Hans-Jörgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112603/ https://www.ncbi.nlm.nih.gov/pubmed/25043824 http://dx.doi.org/10.1186/1129-2377-15-46 |
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