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miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias

BACKGROUND: microRNAs (miRNAs) play both oncogenic and oncostatic roles in leukemia. However, the molecular details underlying miRNA-mediated regulation of their target genes in pediatric B- and T-cell acute lymphoblastic leukemias (ALLs) remain unclear. The present study investigated the relationsh...

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Detalles Bibliográficos
Autores principales: Malik, Deepti, Kaul, Deepak, Chauhan, Nalini, Marwaha, Ram Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112645/
https://www.ncbi.nlm.nih.gov/pubmed/25037230
http://dx.doi.org/10.1186/1476-4598-13-175