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Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication
BACKGROUND: The influenza A virus NS1 protein is a virulence factor and an antagonist of host cell innate immune responses. During virus infection NS1 protein has several functions both in the nucleus and in the cytoplasm and its intracellular localization is regulated by one or two nuclear localiza...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112715/ https://www.ncbi.nlm.nih.gov/pubmed/25023993 http://dx.doi.org/10.1186/1743-422X-11-128 |