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Botulinum toxin‐a treatment reduces human mechanical pain sensitivity and mechanotransduction

The mechanisms underlying the analgesic effects of botulinum toxin serotype A (BoNT‐A) are not well understood. We have tested the hypothesis that BoNT‐A can block nociceptor transduction. Intradermal administration of BoNT‐A to healthy volunteers produced a marked and specific decrease in noxious m...

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Detalles Bibliográficos
Autores principales: Paterson, Kathryn, Lolignier, Stéphane, Wood, John N., McMahon, Stephen B., Bennett, David L. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Liss 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112716/
https://www.ncbi.nlm.nih.gov/pubmed/24550077
http://dx.doi.org/10.1002/ana.24122