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The acute brain response to levodopa heralds dyskinesias in Parkinson disease

OBJECTIVE: In Parkinson disease (PD), long‐term treatment with the dopamine precursor levodopa gradually induces involuntary “dyskinesia” movements. The neural mechanisms underlying the emergence of levodopa‐induced dyskinesias in vivo are still poorly understood. Here, we applied functional magneti...

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Detalles Bibliográficos
Autores principales: Herz, Damian M., Haagensen, Brian N., Christensen, Mark S., Madsen, Kristoffer H., Rowe, James B., Løkkegaard, Annemette, Siebner, Hartwig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Liss 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112717/
https://www.ncbi.nlm.nih.gov/pubmed/24889498
http://dx.doi.org/10.1002/ana.24138