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Brodalumab: an evidence-based review of its potential in the treatment of moderate-to-severe psoriasis

Advances in knowledge regarding the pathogenesis of psoriasis have allowed the development of a new class of agents known as biologic drugs. Data confirm that T helper (Th)17 and interleukin (IL)-17 signaling has a crucial role in the pathogenesis of the disease. High levels of IL-17 and Th17-relate...

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Detalles Bibliográficos
Autores principales: Coimbra, Susana, Figueiredo, Américo, Santos-Silva, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112723/
https://www.ncbi.nlm.nih.gov/pubmed/25093016
http://dx.doi.org/10.2147/CE.S33940