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Decreased basal chloride secretion and altered cystic fibrosis transmembrane conductance regulatory protein, Villin, GLUT5 protein expression in jejunum from leptin-deficient mice

Patients with diabetes and obesity are at increased risk of developing disturbances in intestinal function. In this study, we characterized jejunal function in the clinically relevant leptin-deficient ob/ob mouse, a model of diabetes and obesity. We measured transepithelial short circuit current (I(...

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Detalles Bibliográficos
Autores principales: Leung, Lana, Kang, Jonathan, Rayyan, Esa, Bhakta, Ashesh, Barrett, Brennan, Larsen, David, Jelinek, Ryan, Willey, Justin, Cochran, Scott, Broderick, Tom L, Al-Nakkash, Layla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112754/
https://www.ncbi.nlm.nih.gov/pubmed/25092993
http://dx.doi.org/10.2147/DMSO.S63714