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Decreased basal chloride secretion and altered cystic fibrosis transmembrane conductance regulatory protein, Villin, GLUT5 protein expression in jejunum from leptin-deficient mice

Patients with diabetes and obesity are at increased risk of developing disturbances in intestinal function. In this study, we characterized jejunal function in the clinically relevant leptin-deficient ob/ob mouse, a model of diabetes and obesity. We measured transepithelial short circuit current (I(...

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Detalles Bibliográficos
Autores principales:	Leung, Lana, Kang, Jonathan, Rayyan, Esa, Bhakta, Ashesh, Barrett, Brennan, Larsen, David, Jelinek, Ryan, Willey, Justin, Cochran, Scott, Broderick, Tom L, Al-Nakkash, Layla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112754/ https://www.ncbi.nlm.nih.gov/pubmed/25092993 http://dx.doi.org/10.2147/DMSO.S63714

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