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Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research

Characterizing the relationship between the pharmacokinetics (PK, concentration vs. time) and pharmacodynamics (PD, effect vs. time) is an important tool in the discovery and development of new drugs in the pharmaceutical industry. The purpose of this publication is to serve as a guide for drug disc...

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Detalles Bibliográficos
Autores principales: Tuntland, Tove, Ethell, Brian, Kosaka, Takatoshi, Blasco, Francesca, Zang, Richard Xu, Jain, Monish, Gould, Ty, Hoffmaster, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112793/
https://www.ncbi.nlm.nih.gov/pubmed/25120485
http://dx.doi.org/10.3389/fphar.2014.00174