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Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research
Characterizing the relationship between the pharmacokinetics (PK, concentration vs. time) and pharmacodynamics (PD, effect vs. time) is an important tool in the discovery and development of new drugs in the pharmaceutical industry. The purpose of this publication is to serve as a guide for drug disc...
Autores principales: | Tuntland, Tove, Ethell, Brian, Kosaka, Takatoshi, Blasco, Francesca, Zang, Richard Xu, Jain, Monish, Gould, Ty, Hoffmaster, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112793/ https://www.ncbi.nlm.nih.gov/pubmed/25120485 http://dx.doi.org/10.3389/fphar.2014.00174 |
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