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Novel TPP-riboswitch activators bypass metabolic enzyme dependency

Riboswitches are conserved regions within mRNA molecules that bind specific metabolites and regulate gene expression. TPP-riboswitches, which respond to thiamine pyrophosphate (TPP), are involved in the regulation of thiamine metabolism in numerous bacteria. As these regulatory RNAs are often modula...

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Detalles Bibliográficos
Autores principales: Lünse, Christina E., Scott, Fraser J., Suckling, Colin J., Mayer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112796/
https://www.ncbi.nlm.nih.gov/pubmed/25121086
http://dx.doi.org/10.3389/fchem.2014.00053