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Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle

BACKGROUND: Aberrant DNA methylation in gene promoters is associated with aging and cancer, but the circumstances determining methylation change are unknown. We investigated the impact of lifestyle modulators of colorectal cancer (CRC) risk on the stability of gene promoter methylation in the coloni...

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Detalles Bibliográficos
Autores principales: Noreen, Faiza, Röösli, Martin, Gaj, Pawel, Pietrzak, Jakub, Weis, Stefan, Urfer, Patric, Regula, Jaroslaw, Schär, Primo, Truninger, Kaspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112799/
https://www.ncbi.nlm.nih.gov/pubmed/24973978
http://dx.doi.org/10.1093/jnci/dju161