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The IRP/IRE system in vivo: insights from mouse models

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) post-transcriptionally control the expression of several mRNAs encoding proteins of iron, oxygen and energy metabolism. The mechanism involves their binding to iron responsive elements (IREs) in the untranslated regions of target mRNAs, thereby contro...

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Detalles Bibliográficos
Autores principales: Wilkinson, Nicole, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112806/
https://www.ncbi.nlm.nih.gov/pubmed/25120486
http://dx.doi.org/10.3389/fphar.2014.00176