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FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement

Active positioning of the nucleus is integral to division, migration, and differentiation of mammalian cells(1). Fibroblasts polarizing for migration orient their centrosomes by actin-dependent nuclear movement(2). This nuclear movement depends on nesprin-2 giant (N2G), a large, actin-binding outer...

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Detalles Bibliográficos
Autores principales: Kutscheidt, Stefan, Zhu, Ruijun, Antoku, Susumu, Luxton, Gant W., Stagljar, Igor, Fackler, Oliver T., Gundersen, Gregg G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113092/
https://www.ncbi.nlm.nih.gov/pubmed/24880667
http://dx.doi.org/10.1038/ncb2981