Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

BACKGROUND: Considerable clinical heterogeneity has been well documented amongst individuals with autism spectrum disorders (ASD). However, little is known about the biological mechanisms underlying phenotypic diversity. Genetic studies have established a strong causal relationship between ASD and m...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoming, Xu, Qiong, Bey, Alexandra L, Lee, Yoonji, Jiang, Yong-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113141/
https://www.ncbi.nlm.nih.gov/pubmed/25071925
http://dx.doi.org/10.1186/2040-2392-5-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113141/
https://www.ncbi.nlm.nih.gov/pubmed/25071925
http://dx.doi.org/10.1186/2040-2392-5-30

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