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Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma
BACKGROUND: Multiple myeloma is characterized by clonal expansion of B cells producing monoclonal immunoglobulins or fragments thereof, which can be detected in the serum and/or urine and are ideal target antigens for patient-specific immunotherapies. METHODS: Using phage particles as immunological...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113220/ https://www.ncbi.nlm.nih.gov/pubmed/24885819 http://dx.doi.org/10.1186/1479-5876-12-119 |