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Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal expansion of B cells producing monoclonal immunoglobulins or fragments thereof, which can be detected in the serum and/or urine and are ideal target antigens for patient-specific immunotherapies. METHODS: Using phage particles as immunological...

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Detalles Bibliográficos
Autores principales: Roehnisch, Tim, Then, Cornelia, Nagel, Wolfgang, Blumenthal, Christina, Braciak, Todd, Donzeau, Mariel, Böhm, Thomas, Flaig, Michael, Bourquin, Carole, Oduncu, Fuat S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113220/
https://www.ncbi.nlm.nih.gov/pubmed/24885819
http://dx.doi.org/10.1186/1479-5876-12-119