A Potent HDAC Inhibitor, 1-Alaninechlamydocin, from a Tolypocladium sp. Induces G2/M Cell Cycle Arrest and Apoptosis in MIA PaCa-2 Cells

[Image: see text] The cyclic tetrapeptide 1-alaninechlamydocin was purified from a Great Lakes-derived fungal isolate identified as a Tolypocladium sp. Although the planar structure was previously described, a detailed analysis of its spectroscopic data and biological activity are reported here for...

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Detalles Bibliográficos
Autores principales: Du, Lin, Risinger, April L., King, Jarrod B., Powell, Douglas R., Cichewicz, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113265/
https://www.ncbi.nlm.nih.gov/pubmed/24999749
http://dx.doi.org/10.1021/np500387h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113265/
https://www.ncbi.nlm.nih.gov/pubmed/24999749
http://dx.doi.org/10.1021/np500387h

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