Efficient Expression of Functional (α6β2)(2)β3 AChRs in Xenopus Oocytes from Free Subunits Using Slightly Modified α6 Subunits

Human (α6β2)(α4β2)β3 nicotinic acetylcholine receptors (AChRs) are essential for addiction to nicotine and a target for drug development for smoking cessation. Expressing this complex AChR is difficult, but has been achieved using subunit concatamers. In order to determine what limits expression of...

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Detalles Bibliográficos
Autores principales: Ley, Carson Kai-Kwong, Kuryatov, Alexander, Wang, Jingyi, Lindstrom, Jon Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113361/
https://www.ncbi.nlm.nih.gov/pubmed/25068303
http://dx.doi.org/10.1371/journal.pone.0103244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113361/
https://www.ncbi.nlm.nih.gov/pubmed/25068303
http://dx.doi.org/10.1371/journal.pone.0103244

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