(177)Lu-DOTA-HH1, a Novel Anti-CD37 Radio-Immunoconjugate: A Study of Toxicity in Nude Mice

BACKGROUND: CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia cells (CLL). The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide (177)Lu...

Descripción completa

Detalles Bibliográficos
Autores principales: Repetto-Llamazares, Ada H. V., Larsen, Roy H., Giusti, Anna Maria, Riccardi, Elena, Bruland, Øyvind S., Selbo, Pål Kristian, Dahle, Jostein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113375/
https://www.ncbi.nlm.nih.gov/pubmed/25068508
http://dx.doi.org/10.1371/journal.pone.0103070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113375/
https://www.ncbi.nlm.nih.gov/pubmed/25068508
http://dx.doi.org/10.1371/journal.pone.0103070

Ejemplares similares