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(177)Lu-DOTA-HH1, a Novel Anti-CD37 Radio-Immunoconjugate: A Study of Toxicity in Nude Mice

BACKGROUND: CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia cells (CLL). The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide (177)Lu...

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Detalles Bibliográficos
Autores principales:	Repetto-Llamazares, Ada H. V., Larsen, Roy H., Giusti, Anna Maria, Riccardi, Elena, Bruland, Øyvind S., Selbo, Pål Kristian, Dahle, Jostein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113375/ https://www.ncbi.nlm.nih.gov/pubmed/25068508 http://dx.doi.org/10.1371/journal.pone.0103070

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