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Silencing of Hypoxia-Inducible Factor-1β Induces Anti-Tumor Effects in Hepatoma Cell Lines under Tumor Hypoxia

Dimerization of hypoxia-inducible factor-1 beta (HIF-1β) [aryl hydrocarbon receptor nuclear translocator (ARNT)] with HIF-1α is involved in various aspects of cancer biology, including proliferation and survival under hypoxic conditions. We investigated the in vitro mechanism by which silencing of H...

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Detalles Bibliográficos
Autores principales: Choi, Sung Hoon, Chung, Ae Ri, Kang, Wonseok, Park, Jun Yong, Lee, Mi Sol, Hwang, Shin Won, Kim, Do Young, Kim, Seung Up, Ahn, Sang Hoon, Kim, Seungtaek, Han, Kwang-Hyub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113399/
https://www.ncbi.nlm.nih.gov/pubmed/25068796
http://dx.doi.org/10.1371/journal.pone.0103304