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Silencing of Hypoxia-Inducible Factor-1β Induces Anti-Tumor Effects in Hepatoma Cell Lines under Tumor Hypoxia
Dimerization of hypoxia-inducible factor-1 beta (HIF-1β) [aryl hydrocarbon receptor nuclear translocator (ARNT)] with HIF-1α is involved in various aspects of cancer biology, including proliferation and survival under hypoxic conditions. We investigated the in vitro mechanism by which silencing of H...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113399/ https://www.ncbi.nlm.nih.gov/pubmed/25068796 http://dx.doi.org/10.1371/journal.pone.0103304 |