Pluronic(®) L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse hindlimb ischemia

Intramuscular injection of plasmid DNA (pDNA) to express a therapeutic protein is a promising method for the treatment of many diseases. However, the therapeutic applications are usually hindered by gene delivery efficiency and expression level. In this study, critical factors in a pDNA-based gene t...

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Detalles Bibliográficos
Autores principales: Song, Hongmei, Liu, Sijia, Li, Caixia, Geng, Yanyan, Wang, Gang, Gu, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113404/
https://www.ncbi.nlm.nih.gov/pubmed/25092975
http://dx.doi.org/10.2147/IJN.S65353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113404/
https://www.ncbi.nlm.nih.gov/pubmed/25092975
http://dx.doi.org/10.2147/IJN.S65353

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