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Pluronic(®) L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse hindlimb ischemia
Intramuscular injection of plasmid DNA (pDNA) to express a therapeutic protein is a promising method for the treatment of many diseases. However, the therapeutic applications are usually hindered by gene delivery efficiency and expression level. In this study, critical factors in a pDNA-based gene t...
Autores principales: | Song, Hongmei, Liu, Sijia, Li, Caixia, Geng, Yanyan, Wang, Gang, Gu, Zhongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113404/ https://www.ncbi.nlm.nih.gov/pubmed/25092975 http://dx.doi.org/10.2147/IJN.S65353 |
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