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In Vivo Imaging of Hedgehog Pathway Activation with a Nuclear Fluorescent Reporter
The Hedgehog (Hh) pathway is essential for embryonic development and tissue regeneration, and its dysregulation can lead to birth defects and tumorigenesis. Understanding how this signaling mechanism contributes to these processes would benefit from an ability to visualize Hedgehog pathway activity...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113417/ https://www.ncbi.nlm.nih.gov/pubmed/25068273 http://dx.doi.org/10.1371/journal.pone.0103661 |