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In Vivo Imaging of Hedgehog Pathway Activation with a Nuclear Fluorescent Reporter

The Hedgehog (Hh) pathway is essential for embryonic development and tissue regeneration, and its dysregulation can lead to birth defects and tumorigenesis. Understanding how this signaling mechanism contributes to these processes would benefit from an ability to visualize Hedgehog pathway activity...

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Detalles Bibliográficos
Autores principales: Mich, John K., Payumo, Alexander Y., Rack, Paul G., Chen, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113417/
https://www.ncbi.nlm.nih.gov/pubmed/25068273
http://dx.doi.org/10.1371/journal.pone.0103661