The promise and challenge of high-throughput sequencing of the antibody repertoire

Efforts to determine the antibody repertoire encoded by B cells in the blood or lymphoid organs using high-throughput DNA sequencing technologies have been advancing at an extremely rapid pace and are transforming our understanding of humoral immune responses. Information gained from high-throughput...

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Detalles Bibliográficos
Autores principales: Georgiou, George, Ippolito, Gregory C, Beausang, John, Busse, Christian E, Wardemann, Hedda, Quake, Stephen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113560/
https://www.ncbi.nlm.nih.gov/pubmed/24441474
http://dx.doi.org/10.1038/nbt.2782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113560/
https://www.ncbi.nlm.nih.gov/pubmed/24441474
http://dx.doi.org/10.1038/nbt.2782

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