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Lopinavir inhibits insulin signaling by promoting protein tyrosine phosphatase 1B expression
Treatment with antiretroviral therapy, including protease inhibitors (PIs), may result in metabolic side-effects, for example insulin resistance. The aim of the present study was to investigate the mechanism of the dysregulation of insulin signaling by two PIs, lopinavir and darunavir, by analyzing...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113574/ https://www.ncbi.nlm.nih.gov/pubmed/25120613 http://dx.doi.org/10.3892/etm.2014.1826 |