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Lopinavir inhibits insulin signaling by promoting protein tyrosine phosphatase 1B expression
Treatment with antiretroviral therapy, including protease inhibitors (PIs), may result in metabolic side-effects, for example insulin resistance. The aim of the present study was to investigate the mechanism of the dysregulation of insulin signaling by two PIs, lopinavir and darunavir, by analyzing...
Autores principales: | KITAZAWA, TAKATOSHI, YOSHINO, YUSUKE, SUZUKI, SATOSHI, KOGA, ICHIRO, OTA, YASUO |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113574/ https://www.ncbi.nlm.nih.gov/pubmed/25120613 http://dx.doi.org/10.3892/etm.2014.1826 |
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