Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

Some Clostridium difficile strains produce, in addition to toxins A and B, the binary toxin Clostridium difficile transferase (CDT), which ADP-ribosylates actin and may contribute to the hypervirulence of these strains. The separate binding and translocation component CDTb mediates transport of the...

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Detalles Bibliográficos
Autores principales: Roeder, Maurice, Nestorovich, Ekaterina M., Karginov, Vladimir A., Schwan, Carsten, Aktories, Klaus, Barth, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113744/
https://www.ncbi.nlm.nih.gov/pubmed/25029374
http://dx.doi.org/10.3390/toxins6072097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113744/
https://www.ncbi.nlm.nih.gov/pubmed/25029374
http://dx.doi.org/10.3390/toxins6072097

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