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Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

Some Clostridium difficile strains produce, in addition to toxins A and B, the binary toxin Clostridium difficile transferase (CDT), which ADP-ribosylates actin and may contribute to the hypervirulence of these strains. The separate binding and translocation component CDTb mediates transport of the...

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Detalles Bibliográficos
Autores principales:	Roeder, Maurice, Nestorovich, Ekaterina M., Karginov, Vladimir A., Schwan, Carsten, Aktories, Klaus, Barth, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113744/ https://www.ncbi.nlm.nih.gov/pubmed/25029374 http://dx.doi.org/10.3390/toxins6072097

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