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Flexibilide Obtained from Cultured Soft Coral Has Anti-Neuroinflammatory and Analgesic Effects through the Upregulation of Spinal Transforming Growth Factor-β1 in Neuropathic Rats

Chronic neuroinflammation plays an important role in the development and maintenance of neuropathic pain. The compound flexibilide, which can be obtained from cultured soft coral, possesses anti-inflammatory and analgesic effects in the rat carrageenan peripheral inflammation model. In the present s...

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Detalles Bibliográficos
Autores principales: Chen, Nan-Fu, Huang, Shi-Ying, Lu, Ching-Hsiang, Chen, Chun-Lin, Feng, Chien-Wei, Chen, Chun-Hong, Hung, Han-Chun, Lin, Yen-You, Sung, Ping-Jyun, Sung, Chun-Sung, Yang, San-Nan, Wang, Hui-Min David, Chang, Yu-Chia, Sheu, Jyh-Horng, Chen, Wu-Fu, Wen, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113799/
https://www.ncbi.nlm.nih.gov/pubmed/24979268
http://dx.doi.org/10.3390/md12073792