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The conserved potassium channel filter can have distinct ion binding profiles: Structural analysis of rubidium, cesium, and barium binding in NaK2K

Potassium channels are highly selective for K(+) over the smaller Na(+). Intriguingly, they are permeable to larger monovalent cations such as Rb(+) and Cs(+) but are specifically blocked by the similarly sized Ba(2+). In this study, we used structural analysis to determine the binding profiles for...

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Detalles Bibliográficos
Autores principales: Lam, Yee Ling, Zeng, Weizhong, Sauer, David Bryant, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113894/
https://www.ncbi.nlm.nih.gov/pubmed/25024267
http://dx.doi.org/10.1085/jgp.201411191