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ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2

Dendritic cells (DCs) comprise two major subsets, the interferon (IFN)-producing plasmacytoid DCs (pDCs) and antigen-presenting classical DCs (cDCs). The development of pDCs is promoted by E protein transcription factor E2-2, whereas E protein antagonist Id2 is specifically absent from pDCs. Convers...

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Detalles Bibliográficos
Autores principales: Ghosh, Hiyaa S., Ceribelli, Michele, Matos, Ines, Lazarovici, Allan, Bussemaker, Harmen J., Lasorella, Anna, Hiebert, Scott W., Liu, Kang, Staudt, Louis M., Reizis, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113936/
https://www.ncbi.nlm.nih.gov/pubmed/24980046
http://dx.doi.org/10.1084/jem.20132121