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Loss of nuclear PTEN in HCV-infected human hepatocytes

BACKGROUND: Hepatitis C virus (HCV) infection is a major risk factor for chronic hepatitis and hepatocellular carcinoma (HCC); however, the mechanism of HCV-mediated hepatocarcinogenesis is not well understood. Insufficiency of PTEN tumor suppressor is associated with more aggressive cancers, includ...

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Detalles Bibliográficos
Autores principales: Bao, Wenjie, Florea, Liliana, Wu, Ningbin, Wang, Zhao, Banaudha, Krishna, Qian, Jason, Houzet, Laurent, Kumar, Rakesh, Kumar, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114100/
https://www.ncbi.nlm.nih.gov/pubmed/25075209
http://dx.doi.org/10.1186/1750-9378-9-23