Rag Defects and Thymic Stroma: Lessons from Animal Models

Thymocytes and thymic epithelial cells (TECs) cross-talk is essential to support T cell development and preserve thymic architecture and maturation of TECs and Foxp3(+) natural regulatory T cells. Accordingly, disruption of thymic lymphostromal cross-talk may have major implications on the thymic me...

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Detalles Bibliográficos
Autores principales: Marrella, Veronica, Poliani, Pietro Luigi, Notarangelo, Luigi Daniele, Grassi, Fabio, Villa, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114104/
https://www.ncbi.nlm.nih.gov/pubmed/25076946
http://dx.doi.org/10.3389/fimmu.2014.00259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114104/
https://www.ncbi.nlm.nih.gov/pubmed/25076946
http://dx.doi.org/10.3389/fimmu.2014.00259

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