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Single cell segmental aneuploidy detection is compromised by S phase

BACKGROUND: Carriers of balanced translocations are at high risk for unbalanced gametes which can result in recurrent miscarriages or birth defects. Preimplantation genetic diagnosis (PGD) is often offered to select balanced embryos. This selection is currently mainly performed by array CGH on blast...

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Detalles Bibliográficos
Autores principales: Dimitriadou, Eftychia, Van der Aa, Niels, Cheng, Jiqiu, Voet, Thierry, Vermeesch, Joris R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114140/
https://www.ncbi.nlm.nih.gov/pubmed/25075223
http://dx.doi.org/10.1186/1755-8166-7-46