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Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy

The incidence of dementia is increasing at an alarming rate, and has become a major public health concern. Alzheimer disease (AD) is the most common form of dementia and is characterized by progressive cognitive impairment. In addition to classical neuropathological features such as amyloid plaques...

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Detalles Bibliográficos
Autores principales: Takeda, Shuko, Sato, Naoyuki, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114193/
https://www.ncbi.nlm.nih.gov/pubmed/25120476
http://dx.doi.org/10.3389/fnagi.2014.00171