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NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

The mitochondrial matrix GTPase NOA1 is a nuclear encoded protein, essential for mitochondrial protein synthesis, oxidative phosphorylation and ATP production. Here, we demonstrate that newly translated NOA1 protein is imported into the nucleus, where it localizes to the nucleolus and interacts with...

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Detalles Bibliográficos
Autores principales: Al-Furoukh, Natalie, Kardon, Julia R., Krüger, Marcus, Szibor, Marten, Baker, Tania A., Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114565/
https://www.ncbi.nlm.nih.gov/pubmed/25072814
http://dx.doi.org/10.1371/journal.pone.0103141