Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G(1) cell cycle arrest in A549 cells

Telomerase Cajal body protein 1 (TCAB1) is a telomerase holoenzyme, which is markedly enriched in Cajal bodies (CBs) and facilitates the recruitment of telomerase to CBs in the S phase of the cell cycle. This recruitment is dependent on TCAB1 binding to a telomerase RNA component. The majority of ca...

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Detalles Bibliográficos
Autores principales: YUAN, PING, WANG, ZHITIAN, LV, WANG, PAN, HUI, YANG, YUNHAI, YUAN, XIAOSHUAI, HU, JIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114580/
https://www.ncbi.nlm.nih.gov/pubmed/25120649
http://dx.doi.org/10.3892/ol.2014.2306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114580/
https://www.ncbi.nlm.nih.gov/pubmed/25120649
http://dx.doi.org/10.3892/ol.2014.2306

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