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Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G(1) cell cycle arrest in A549 cells
Telomerase Cajal body protein 1 (TCAB1) is a telomerase holoenzyme, which is markedly enriched in Cajal bodies (CBs) and facilitates the recruitment of telomerase to CBs in the S phase of the cell cycle. This recruitment is dependent on TCAB1 binding to a telomerase RNA component. The majority of ca...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114580/ https://www.ncbi.nlm.nih.gov/pubmed/25120649 http://dx.doi.org/10.3892/ol.2014.2306 |