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Inflammatory cytokines induce vascular endothelial growth factor-C expression in melanoma-associated macrophages and stimulate melanoma lymph node metastasis

Lymph node colonization by tumor cells is one of the key determinants of melanoma staging and prognosis, and tumor-associated macrophages (TAMs) are the predominant type of inflammatory cell in the tumor environment which secretes vascular endothelial growth factor (VEGF)-C, the most potent lymphang...

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Detalles Bibliográficos
Autores principales: PEPPICELLI, SILVIA, BIANCHINI, FRANCESCA, CALORINI, LIDO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114605/
https://www.ncbi.nlm.nih.gov/pubmed/25120672
http://dx.doi.org/10.3892/ol.2014.2297