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Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage
Selenocysteine (Sec) is encoded by an UGA codon with the help of a SECIS element present in selenoprotein mRNAs. SECIS-binding protein (SBP2/SCBP-2) mediates Sec insertion, but the roles of its domains and the impact of its deficiency on Sec insertion are not fully understood. We used Caenorhabditis...
Autores principales: | Otero, Lucía, Romanelli-Cedrez, Laura, Turanov, Anton A., Gladyshev, Vadim N., Miranda-Vizuete, Antonio, Salinas, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114682/ https://www.ncbi.nlm.nih.gov/pubmed/24817701 http://dx.doi.org/10.1261/rna.043877.113 |
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