Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape

The hepatitis delta virus (HDV) ribozyme is a member of the class of small, self-cleaving catalytic RNAs found in a wide range of genomes from HDV to human. Both pre- and post-catalysis (precursor and product) crystal structures of the cis-acting genomic HDV ribozyme have been determined. These stru...

Descripción completa

Detalles Bibliográficos
Autores principales: Sripathi, Kamali N., Tay, Wendy W., Banáš, Pavel, Otyepka, Michal, Šponer, Jiří, Walter, Nils G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114689/
https://www.ncbi.nlm.nih.gov/pubmed/24854621
http://dx.doi.org/10.1261/rna.044982.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114689/
https://www.ncbi.nlm.nih.gov/pubmed/24854621
http://dx.doi.org/10.1261/rna.044982.114

Ejemplares similares