Identification of Polyketide Inhibitors Targeting 3-Dehydroquinate Dehydratase in the Shikimate Pathway of Enterococcus faecalis

Due to the emergence of resistance toward current antibiotics, there is a pressing need to develop the next generation of antibiotics as therapeutics against infectious and opportunistic diseases of microbial origins. The shikimate pathway is exclusive to microbes, plants and fungi, and hence is an...

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Detalles Bibliográficos
Autores principales: Cheung, Vivian Wing Ngar, Xue, Bo, Hernandez-Valladares, Maria, Go, Maybelle Kho, Tung, Alvin, Aguda, Adeleke H., Robinson, Robert C., Yew, Wen Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114755/
https://www.ncbi.nlm.nih.gov/pubmed/25072253
http://dx.doi.org/10.1371/journal.pone.0103598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114755/
https://www.ncbi.nlm.nih.gov/pubmed/25072253
http://dx.doi.org/10.1371/journal.pone.0103598

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