Cargando…
Timely Activation of Budding Yeast APC(Cdh1) Involves Degradation of Its Inhibitor, Acm1, by an Unconventional Proteolytic Mechanism
Regulated proteolysis mediated by the ubiquitin proteasome system is a fundamental and essential feature of the eukaryotic cell division cycle. Most proteins with cell cycle-regulated stability are targeted for degradation by one of two related ubiquitin ligases, the Skp1-cullin-F box protein (SCF)...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114781/ https://www.ncbi.nlm.nih.gov/pubmed/25072887 http://dx.doi.org/10.1371/journal.pone.0103517 |