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Timely Activation of Budding Yeast APC(Cdh1) Involves Degradation of Its Inhibitor, Acm1, by an Unconventional Proteolytic Mechanism

Regulated proteolysis mediated by the ubiquitin proteasome system is a fundamental and essential feature of the eukaryotic cell division cycle. Most proteins with cell cycle-regulated stability are targeted for degradation by one of two related ubiquitin ligases, the Skp1-cullin-F box protein (SCF)...

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Detalles Bibliográficos
Autores principales:	Melesse, Michael, Choi, Eunyoung, Hall, Hana, Walsh, Michael J., Geer, M. Ariel, Hall, Mark C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114781/ https://www.ncbi.nlm.nih.gov/pubmed/25072887 http://dx.doi.org/10.1371/journal.pone.0103517

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