SIRT2 Deficiency Modulates Macrophage Polarization and Susceptibility to Experimental Colitis

BACKGROUND: SIRT2 belongs to a highly conserved family of NAD(+)-dependent deacylases, consisting of seven members (SIRT1–SIRT7), which vary in subcellular localizations and have substrates ranging from histones to transcription factors and enzymes. Recently SIRT2 was revealed to play an important r...

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Detalles Bibliográficos
Autores principales: Lo Sasso, Giuseppe, Menzies, Keir Joe, Mottis, Adrienne, Piersigilli, Alessandra, Perino, Alessia, Yamamoto, Hiroyasu, Schoonjans, Kristina, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114785/
https://www.ncbi.nlm.nih.gov/pubmed/25072851
http://dx.doi.org/10.1371/journal.pone.0103573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114785/
https://www.ncbi.nlm.nih.gov/pubmed/25072851
http://dx.doi.org/10.1371/journal.pone.0103573

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