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SIRT2 Deficiency Modulates Macrophage Polarization and Susceptibility to Experimental Colitis
BACKGROUND: SIRT2 belongs to a highly conserved family of NAD(+)-dependent deacylases, consisting of seven members (SIRT1–SIRT7), which vary in subcellular localizations and have substrates ranging from histones to transcription factors and enzymes. Recently SIRT2 was revealed to play an important r...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114785/ https://www.ncbi.nlm.nih.gov/pubmed/25072851 http://dx.doi.org/10.1371/journal.pone.0103573 |