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Gene Expression Analysis Suggests Bone Development-Related Genes GDF5 and DIO2 Are Involved in the Development of Kashin-Beck Disease in Children Rather than Adults

OBJECTIVE: To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD). METHODS: 12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD child...

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Detalles Bibliográficos
Autores principales: Wen, Yan, Zhang, Feng, Li, Chunyan, He, Shulan, Tan, Wuhong, Lei, Yanxia, Zhang, Qiang, Yu, Hanjie, Zheng, Jingjing, Guo, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114804/
https://www.ncbi.nlm.nih.gov/pubmed/25072641
http://dx.doi.org/10.1371/journal.pone.0103618